Home > Review Articles > Ethnic disparities in breast cancer survival: How much is explained by screening, tumour severity, biology, treatment, co-morbidities and demographics?

Ethnic disparities in breast cancer survival: How much is explained by screening, tumour severity, biology, treatment, co-morbidities and demographics?

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Authors:
Summary:

41,020 women aged 68 years or older and with a first time incident breast cancer diagnosed between 1994 and 1999 were identified from the Surveillance, Epidemiology, and End Results (SEER) database. The authors calculated racial and ethnic differences in breast cancer survival, adjusting for factors including demographic variables, mammographic screening interval prior to diagnosis, breast cancer characteristics at diagnosis, markers of biology, treatment and co-morbidity. Breast cancer specific mortality amongst women diagnosed with stage II or II breast cancer was significantly higher for African American women (HR 1.3) and significantly lower for Asian women (HR 0.63) in comparison to Caucasian women, whereas Hispanic women had non-significantly lower rates (HR 0.90) compared to Caucasian women. The author notes that that “although screening, biology and treatment do play a role, race/ethnicity appears to have an independent effect, particularly for African American women.”

Comment:
Dr Curtis (Te Arawa) worked on this project as part of her Harkness fellowship in 2004-5. Once again she has tried to untangle the reasons for ethnic disparities in health outcomes, this time for women living in the US with breast cancer. Dr Curtis has provided evidence here that the reasons often accepted by many health professionals and providers to explain ethnic disparities (such as interval to screening, tumour characteristics, treatment and co morbidity) are not adequate and further research into this complex issue is necessary. http://www.conference.co.nz/index.cfm/pridoc2006/Programme
Independent commentary by Dr. Matire Hardwood

Dr Matire Harwood (Ngapuhi) has worked in Hauora Māori, primary health and rehabilitation settings as clinician and researcher since graduating from Auckland Medical School in 1994. She also holds positions on a number of boards, committees and advisory groups including the Health Research Council. Matire lives in Auckland with her whānau including partner Haunui and two young children Te Rangiura and Waimarie.

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