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Metformin adherence in patients with type 2 diabetes and its association with glycated haemoglobin levels

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Summary:

Ethnic disparity in metformin prescribing was uncovered in an investigation of metformin adherence in patients with type 2 diabetes. Prescription and dispensing data during the period from October 2016 to March 2018 were collected for 1595 patients from 10 general practices. The mean medication possession ratio was 0.87. Optimal medication cover for ≥80% of days was achieved by 63.8% of Māori vs 81.2% of European patients. Prescription adherence did not differ by ethnicity, but significantly fewer Māori patients received a prescription for metformin (p=0.002) leading to an overall reduction in metformin coverage for Māori patients. Adherence to metformin was associated with a 3.2 mmol/mol reduction in HbA1c (p<0.01).

Comment:
Too often we hear the ‘non-compliance’ narrative when attempting to explain inequities in outcomes for long-term conditions such as diabetes (spoiler alert, it’s not true!). Really useful to have this paper in our ‘resource kete’ and pull it out when needed, to counter incorrect assumptions.
Reference: J Prim Health Care. 2020;12(4):318-326.
Independent commentary by Dr. Matire Hardwood

Dr Matire Harwood (Ngapuhi) has worked in Hauora Māori, primary health and rehabilitation settings as clinician and researcher since graduating from Auckland Medical School in 1994. She also holds positions on a number of boards, committees and advisory groups including the Health Research Council. Matire lives in Auckland with her whānau including partner Haunui and two young children Te Rangiura and Waimarie.

Research Review publications are intended for New Zealand health professionals.

Disclaimer: This publication is not intended as a replacement for regular medical education but to assist in the process. The reviews are a summarised interpretation of the published study and reflect the opinion of the writer rather than those of the research group or scientific journal. It is suggested readers review the full trial data before forming a final conclusion on its merits.

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