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Pediatric invasive meningococcal disease, Auckland, New Zealand (Aotearoa), 2004-2020

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Authors:
Summary:

A review of laboratory-confirmed invasive meningococcal disease cases in Auckland between January 2004 and December 2020 has shown that Māori and Pasifika children are disproportionately affected, and that serogroup B is by far the most common strain. There were 319 cases of meningococcal disease in 318 children aged <15 years during the review period, of which 4.1% died and 23.6% of those with follow-up data experienced sequelae. As well as Māori and Pasifika children, those living in the most deprived areas were also over-represented. Serogroup B meningococcal disease was found in 81% of cases, serogroup W in 8.6% of cases, serogroup C in 6.3% of cases, and serogroup Y in 3.7% of cases. Bacteraemia was present in 79% of cases and meningitis in 63.9%. The New Zealand National Immunisation Schedule should include vaccination against serogroup B meningococcal disease to address health inequities for Māori and Pasifika children, concluded the study authors.

Comment:
Immunisation is an incredibly important tool for preventing infectious diseases, but particularly those associated with inequitable rates of death and disability for Māori compared with non-Māori. Measles and meningitis are two examples. It is good to see that vaccination against serogroup B meningococcal disease is now funded for infants, immunocompromised individuals and those aged 13-25 years living in close quarters.
Reference: Emerg Infect Dis. 2023;29(4):686-695.
Independent commentary by Dr. Matire Hardwood

Dr Matire Harwood (Ngapuhi) has worked in Hauora Māori, primary health and rehabilitation settings as clinician and researcher since graduating from Auckland Medical School in 1994. She also holds positions on a number of boards, committees and advisory groups including the Health Research Council. Matire lives in Auckland with her whānau including partner Haunui and two young children Te Rangiura and Waimarie.

Research Review publications are intended for New Zealand health professionals.

Disclaimer: This publication is not intended as a replacement for regular medical education but to assist in the process. The reviews are a summarised interpretation of the published study and reflect the opinion of the writer rather than those of the research group or scientific journal. It is suggested readers review the full trial data before forming a final conclusion on its merits.

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