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Acute aortic syndrome: nationwide study of epidemiology, management, and outcomes

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Summary:

Mortality after acute aortic syndrome (AAS) has remained high over the last decade, according to a national population-based study. A total of 1295 patients presenting to hospital with an index admission of AAS (61% type A and 38% type B) between 2010 and 2020 were retrospectively assessed. Hospital records were supplemented by information from the National Mortality Collection and the Australasian Vascular Audit. Between 2010 and 2018, 290 patients died out of hospital. The overall incidence of aortic dissection, including out-of-hospital cases, was 3.13 (95% confidence interval [CI] 2.96-3.30) per 100 000 person-years, and this increased by an average of 3% (95% CI 1-6%) per year after adjustment for age and sex, driven by increasing type A cases. Age standardised disease rates were higher in men, and in Māori and Pacific populations. Overall rates of 30-day mortality were 31.9% in patients with type A disease and 9.7% in those with type B disease, and did not change significantly over the study period. Management strategies also remained constant over time. The study authors noted that work is needed to reduce ethnic disparities in rates of AAS.

Comment:
As with other cardiovascular diseases, there are significant inequities in AAS and other aortic diseases between Māori and non-Māori. A recent pilot has tested the effectiveness of screening for aortic disease in older Māori. This is a promising area because, as the authors conclude, a focus on reducing risk and early management appears to be the best way to reduce disparities.
Reference: Br J Surg. 2023;110(9):1197-1205.
Independent commentary by Dr. Matire Hardwood

Dr Matire Harwood (Ngapuhi) has worked in Hauora Māori, primary health and rehabilitation settings as clinician and researcher since graduating from Auckland Medical School in 1994. She also holds positions on a number of boards, committees and advisory groups including the Health Research Council. Matire lives in Auckland with her whānau including partner Haunui and two young children Te Rangiura and Waimarie.

Research Review publications are intended for New Zealand health professionals.

Disclaimer: This publication is not intended as a replacement for regular medical education but to assist in the process. The reviews are a summarised interpretation of the published study and reflect the opinion of the writer rather than those of the research group or scientific journal. It is suggested readers review the full trial data before forming a final conclusion on its merits.

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