A systematic review and meta-analysis has shown that racism is associated with negative physical health and biomarker outcomes relating to multiple physiological systems and biological processes in childhood and adolescence. A total of 42 studies focused on physical health or biomarker outcomes were identified from Medline, PsycINFO, PubMed, and ERIC. Minimal to moderate positive associations were found between racism and C-reactive protein, interleukin-6, body mass index (BMI), obesity, systolic blood pressure, salivary cortisol, asthma, and somatic symptoms. Marginal positive associations were found between racism and tumour necrosis factor-α, cortisol collected via saliva, urine and hair, BMI-z score, and diastolic blood pressure. The study authors noted that collective and structural changes to eliminate racism and create a healthy and equitable future for all children and youth are urgently required.