A systematic review was conducted to examine the burden of stomach cancer among indigenous peoples worldwide. Increased rates of stomach cancer incidence and mortality were observed in almost all indigenous peoples considered (indigenous Australians, Māori, circumpolar indigenous peoples, native Americans and Alaskan natives, and the Chilean Mapuche) when compared to the corresponding non-indigenous population in the same region or countries, particularly among the Inuit in the circumpolar region (standardised incidence ratios; males 3.9, females 3.6) and Māori (males: 2.2, females: 3.2).