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Do Māori and Pacific Islander men present with more advanced prostate cancer than European New Zealand men? An analysis of 486 men undergoing biopsy in Auckland

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Authors:
Summary:

This retrospective audit analysed data from the Auckland Hospital Urology Service database of all men presenting there for a first prostate biopsy in 2005 and 2006. The study aim was to determine whether Māori and Pacific Islander men in Auckland present with more advanced prostate cancer at diagnosis than New Zealand European or European men. Ethnicity was coded from self-identification codes on hospital databases. No appreciable difference was observed when Māori and Pacific Islander men were compared with European men for median PSA level (13.30 vs 12.55 ng/mL); median Gleason score (7 and 7), mean Gleason score (7.0 vs 6.9) or the proportion of Gleason Score 7 or 8–10. Likewise, the rates of metastatic disease did not differ at presentation (11.5% vs 7.8%). However, there appeared to be a significant difference in the proportion of Māori and Pacific Islanders presenting with palpable disease compared with European men (67.2% vs 53.3%; p=0.042). The crude population biopsy rate per 100,000 was similar for Māori and Pacific Islander and European men (560 vs 547).

Comment:
An important study given the significant inequalities in survival rates for prostate cancer between Māori and non-Māori. Interestingly, whilst ‘late presentation’ is considered to be a major contributing factor to survival disparities between Māori and non-Māori, these findings contest its occurrence. A review of treatment rates by ethnicity is required.
Reference: BJU Int. 2011;107 Suppl 3:27-32.
Independent commentary by Dr. Matire Hardwood

Dr Matire Harwood (Ngapuhi) has worked in Hauora Māori, primary health and rehabilitation settings as clinician and researcher since graduating from Auckland Medical School in 1994. She also holds positions on a number of boards, committees and advisory groups including the Health Research Council. Matire lives in Auckland with her whānau including partner Haunui and two young children Te Rangiura and Waimarie.

Research Review publications are intended for New Zealand health professionals.

Disclaimer: This publication is not intended as a replacement for regular medical education but to assist in the process. The reviews are a summarised interpretation of the published study and reflect the opinion of the writer rather than those of the research group or scientific journal. It is suggested readers review the full trial data before forming a final conclusion on its merits.

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