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These researchers discuss the evidence from preclinical and clinical studies of placental gene expression responses to maternal stress such as hypoxia, protein deficiency, and caloric excess. The paper discusses these gene expression changes within a framework of the biochemical pathways and molecular mechanisms, arguing that stresses to the maternal organism can result in alterations of great biological and epigenetic importance to the developing embryo and foetus.
Dr Matire Harwood (Ngapuhi) has worked in Hauora Māori, primary health and rehabilitation settings as clinician and researcher since graduating from Auckland Medical School in 1994. She also holds positions on a number of boards, committees and advisory groups including the Health Research Council. Matire lives in Auckland with her whānau including partner Haunui and two young children Te Rangiura and Waimarie.
Research Review publications are intended for New Zealand health professionals.
Disclaimer: This publication is not intended as a replacement for regular medical education but to assist in the process. The reviews are a summarised interpretation of the published study and reflect the opinion of the writer rather than those of the research group or scientific journal. It is suggested readers review the full trial data before forming a final conclusion on its merits.
A study of pregnant or recently pregnant Māori and Pasifika women found that those who
Maternal health inequity is strongly associated with a range of socioeconomic and health determinants, according
Pharmacy funding for pertussis vaccination during pregnancy increases uptake, particularly for Māori women, according to
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