Māori and Pacific populations in deprived areas experience high rates of mental health-related callouts to the ambulance service, according to a cross-sectional study. The study analysed data from electronic patient report forms collected between July 2022 and June 2023, and identified 26,847 mental health-related callouts from the Aotearoa New Zealand Paramedic Care Collection. Among individuals aged <24 years, 31.9% of callouts were Māori and 29.3% were Pacific peoples, compared with 19.1% for non-Māori, non-Pacific peoples (NMNPP; p<0.001). Among individuals living in the most deprived areas, Māori and Pacific peoples accounted for 47.7% and 49.9% of callouts, respectively, compared with 24.5% of NMNPP (p<0.001).