This analysis of endoscopy non-attendance rates and associated factors examined data from 58,434 consecutive endoscopy appointments at the Canterbury (n=33,697) and Auckland (n= 24,737) DHBs during a 5-year period (1 April 2012 to 31 March 2017). The following procedures were included: gastroscopy, colonoscopy and endoscopic retrograde cholangiopancreatography. Overall, 2,694 (4.6%) appointments were not attended. In multivariate analysis, Māori (OR 3.0; 95% CI, 2.63 to 3.42) and Pacific Peoples (OR 3.1; 95% CI, 2.7 to 3.55) were significantly more likely than Europeans to miss appointments. Patients residing in the socioeconomically most deprived areas (NZDep decile 10) had higher rates of non-attendance compared with those from NZDep decile 1 (OR 2.13; 95% CI, 1.72 to 2.63). Non-attendance rates were also higher among males (OR 1.43; 95% CI, 1.32 to 1.56) and among the Auckland DHB patients (2.28; 2.08 to 2.50).