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Prospective surveillance of hospitalisations associated with varicella in New Zealand children

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Summary:

Data from the New Zealand Paediatric Surveillance Unit (NZPSU) were analysed for this investigation into the hospitalisation burden of varicella. Cases (0–14 years) were defined as varicella and post-varicella complications requiring hospitalisation, including stroke syndromes where varicella occurred in the preceding 6 months, reported to the NZPSU between 1 November 2011 and 31 October 2013. Of a total of 178 notifications, 144 were confirmed cases. The hospitalisation rate was 8.3/100,000 children per year, with over-representation among Māori and Pacific Island (PI) children, who accounted for 74% of hospitalisations and both had significantly higher incidence rate ratios (2.8 and 3.9, respectively) compared with European children (p<0.01). Complications included infection (75%), respiratory (11%), neurological (11%), electrolyte disturbance (6%) and haemorrhagic varicella (4%). Nine percent were immunocompromised. Median duration of hospital admission was 4 days, with 9% requiring intensive care admission. There were no reported deaths; however, 19% had ongoing problems at discharge.

Comment:
I know a few Māori whānau who, having experienced the significant morbidity that can occur with varicella infections (chickenpox) in their older children, self-funded the varicella vaccination for their younger kids. As the authors suggest, the inclusion in NZ’s immunisation schedule has the potential to reduce health inequities between Māori and non-Māori children.
Reference: J Paediatr Child Health. 2015;51(11):1078-83
Independent commentary by Dr. Matire Hardwood

Dr Matire Harwood (Ngapuhi) has worked in Hauora Māori, primary health and rehabilitation settings as clinician and researcher since graduating from Auckland Medical School in 1994. She also holds positions on a number of boards, committees and advisory groups including the Health Research Council. Matire lives in Auckland with her whānau including partner Haunui and two young children Te Rangiura and Waimarie.

Research Review publications are intended for New Zealand health professionals.

Disclaimer: This publication is not intended as a replacement for regular medical education but to assist in the process. The reviews are a summarised interpretation of the published study and reflect the opinion of the writer rather than those of the research group or scientific journal. It is suggested readers review the full trial data before forming a final conclusion on its merits.

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