In this 12-month pilot investigation into the cultural acceptability of home-based remote telemonitoring among patients with chronic health conditions, there were no clear differences in quality of life at the end of the trial among those in the control group, whereas the telehealth group showed a consistent trend towards improved quality of life on several instruments, including the SF-36, the St George Respiratory Questionnaire and the K10 questionnaire; the improvement in the latter was significant. Hospitalisations were reduced in both the control (–19%) and telehealth group (–25%). Patient interviews indicated that the technology was acceptable to most patients and their families, including Māori.