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Risk of stomach cancer in Aotearoa/New Zealand: A Māori population based case-control study

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Summary:

Rates of stomach cancer are disproportionate amongst New Zealand Māori compared to non-Māori. These researchers sought to better understand the reasons for this phenomenon and to identify priorities for prevention. 165 Māori stomach cancer cases from the New Zealand Cancer Registry between 1 February 2009 and 31 October 2013 were matched by 5-year age bands with 480 Māori controls randomly selected from the New Zealand electoral roll. Nearly half (47.9%) of cases were of the diffuse subtype. There were differences in the distribution of risk factors between cases and controls. In logistic regression analysis, stomach cancer risk was strongly increased by having >2 people sharing a bedroom in childhood (OR 3.30; 95% CI, 1.95 to 5.59), testing for Helicobacter pylori (OR 12.17; 95% CI, 6.15 to 24.08), being an ex-smoker (OR 2.26; 95% CI, 1.44 to 3.54) and exposure to environmental tobacco smoke in adulthood (OR 3.29; 95% CI, 1.94 to 5.59).

Comment:
This paper is important for a couple of reasons. Firstly, it is the first national study of stomach cancer in any indigenous population. It also provides useful information about risk factors and screening criteria for stomach cancer.
Reference: PLoS One. 2017;12(7):e0181581
Independent commentary by Dr. Matire Hardwood

Dr Matire Harwood (Ngapuhi) has worked in Hauora Māori, primary health and rehabilitation settings as clinician and researcher since graduating from Auckland Medical School in 1994. She also holds positions on a number of boards, committees and advisory groups including the Health Research Council. Matire lives in Auckland with her whānau including partner Haunui and two young children Te Rangiura and Waimarie.

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