Home > Review Articles > Cancer > Patterns of axillary lymph node metastases and recurrent disease in grade 1 breast cancer in a New Zealand cohort: Does ethnicity matter?

Patterns of axillary lymph node metastases and recurrent disease in grade 1 breast cancer in a New Zealand cohort: Does ethnicity matter?

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Summary:

Using data from the Auckland Breast Cancer Registry (ABCR) and the Waikato Breast Cancer Registry (WBCR), these researchers identified 2857 women newly diagnosed with grade 1 primary invasive breast cancer between 1 June 2000 and 31 May 2013. Almost one-fifth (19.0%) had axillary lymph node involvement, and recurrent disease (locoregional or distant) developed in 5.1%. Pacific and Māori women were more likely than NZ European women to have larger tumours and lymphovascular invasion (LVI). Predictors for axillary node involvement were tumour size >10 mm, LVI and non-screen detected cancers. Factors found to predict recurrent and/or metastatic disease were tumour size >10 mm, lobular carcinoma and breastconserving surgery without radiotherapy. Ethnicity did not independently predict axillary nodal involvement, recurrent and/or metastatic disease, or breast cancer-specific mortality in this patient population.

Comment:
Hopefully the results will get breast cancer services to focus on early diagnosis and better management rather than genetic differences.
Reference: Cancer Epidemiol. 2015;39(6):994-9
Independent commentary by Dr. Matire Hardwood

Dr Matire Harwood (Ngapuhi) has worked in Hauora Māori, primary health and rehabilitation settings as clinician and researcher since graduating from Auckland Medical School in 1994. She also holds positions on a number of boards, committees and advisory groups including the Health Research Council. Matire lives in Auckland with her whānau including partner Haunui and two young children Te Rangiura and Waimarie.

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